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O5380

Supelco

奥昔卡因

analytical standard

同義詞:

2-羟乙基亚氨基双(N-[α,α-二甲基苯乙基]-N-甲基乙酰胺), 阿塞赛因

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About This Item

經驗公式(希爾表示法):
C28H41N3O3
CAS號碼:
分子量::
467.64
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

格式

neat

SMILES 字串

CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2

InChI

1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3

InChI 密鑰

FTLDJPRFCGDUFH-UHFFFAOYSA-N

一般說明

Oxethazaine is a topical anesthetic, administered as an antacid for treating pain associated with duodenal ulcer, esophagitis and gastritis.

應用

Oxethazaine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Yasusuke Masuda
Journal of pharmacological sciences, 100(3), 167-174 (2006-03-07)
The liver has an intricate microvascular system that allows homogenous perfusion throughout the organ. However, the regulatory mechanisms of intrahepatic circulation are still unclear, and the effects of drugs on this system have rarely been reported. Oxethazaine, a topical anesthetic
A Zanni et al.
Current medical research and opinion, 10(2), 128-134 (1986-01-01)
A double-blind study was carried out in 40 patients with typical ulcer pain and suffering from gastric or duodenal ulcer to compare the pain-relieving efficacy of oxethazaine/magnesium and aluminium hydroxide mixture with that of the antacid combination alone. Patients took
[Resorption of cyclosporin administered by oral route to renal transplant patients. Influence of breakfast and an antacid drug].
F Penouil et al.
Therapie, 43(1), 15-19 (1988-01-01)
R Yasuno et al.
Biological & pharmaceutical bulletin, 21(12), 1294-1299 (1999-01-09)
Oxethazaine (OXZ), a potent topical anesthetic, was found to induce red blood cell (RBC) lysis in vitro, depending upon concentrations of OXZ, RBC and Ca2+. In a 2% RBC suspension, 100 microM OXZ caused almost complete hemolysis in the presence
T Takagi et al.
The American journal of physiology, 255(4 Pt 1), G522-G528 (1988-10-01)
Celiac and superior mesenteric arterial blood flows were measured simultaneously in conscious beagle dogs. The responses to food were completely different between the two arteries. Celiac flow increased quickly to 180-200% of the control 2 min after food but started

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