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Merck
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M0513

Supelco

醋酸甲地孕酮

analytical standard, for drug analysis

同義詞:

17α-乙酰氧基-6-甲基孕甾-4,6-二烯-3,20-二酮, 17α-羟基-6-甲基-6-去氢孕酮 17-乙酸酯, 17α-羟基-6-甲基孕甾-4,6-二烯-3,20-二酮 17-乙酸酯, 甲地孕酮 17-乙酸酯

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About This Item

經驗公式(希爾表示法):
C24H32O4
CAS號碼:
分子量::
384.51
Beilstein:
1917291
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

化驗

≥99% (HPLC)

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
veterinary

格式

neat

SMILES 字串

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C

InChI

1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

InChI 密鑰

RQZAXGRLVPAYTJ-GQFGMJRRSA-N

基因資訊

human ... PGR(5241)

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一般說明

Megestrol acetate is a commonly used synthetically prepared glucosteroid, which possesses anti-inflammatory property.

應用

Megestrol acetate may be used as a reference standard for the determination of megestrol acetate in human serum using reversed-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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存取文件庫

Handbook of Clinical Nutrition and Aging (2009)
Determination of megestrol acetate and cyproterone acetate in serum of patients with advanced breast cancer by high-performance liquid chromatography
Dikkeschei.D.L, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 529, 145-154 (1990)
Yo Han Kim et al.
Clinical therapeutics, 37(2), 439-447 (2014-12-03)
Megestrol acetate oral suspension is an appetite stimulant indicated for cachexia. It is available in a conventional formulation and as a nanocrystal dispersion. The aim of this study was to compare the tolerability and pharmacokinetics of these formulations under fed
Navdha Mittal et al.
PloS one, 9(10), e110410-e110410 (2014-10-24)
Resistance to progestin treatment is a major hurdle in the treatment of advanced and reoccurring endometrial cancer. Fenretinide is a synthetic retinoid that has been evaluated in clinical trials as a cancer therapeutic and chemo-preventive agent. Fenretinide has been established
Francisco J Prado-Prado et al.
Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27)
There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability with which a drug is active against

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