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Merck
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32438

Supelco

帕苯达唑

VETRANAL®, analytical standard

同義詞:

(5-丁基-1H-苯并咪唑-2-基)氨基甲酸甲酯, 5(6)-丁基-2-苯并咪唑氨基甲酸甲酯

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About This Item

經驗公式(希爾表示法):
C13H17N3O2
CAS號碼:
分子量::
247.29
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1

InChI

1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)

InChI 密鑰

YRWLZFXJFBZBEY-UHFFFAOYSA-N

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一般說明

Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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P Tejada et al.
Veterinary parasitology, 24(3-4), 269-274 (1987-05-01)
Determinations were made of the inhibitory activities of four benzimidazole anthelmintics (Albendazole, Parbendazole, Mebendazole and Thiabendazole) on purified extracts of cytoplasmic and mitochondrial malate dehydrogenase obtained from Ascaris suum, Fasciola hepatica and Moniezia expansa. The highest percentage inhibitions were exhibited
Inhibition of secretion of proteins and triacylglycerol from isolated rat hepatocytes mediated by benzimidazole carbamate antimicrotubule agents.
C R Birkett et al.
Biochemical pharmacology, 30(12), 1629-1633 (1981-06-15)
J C Havercroft et al.
Journal of cell science, 49, 195-204 (1981-06-01)
We have shown that the benzimidazole carbamate, parbendazole, is a potent inhibitor of microtubule assembly in vitro and in vivo. Radiolabelled parbendazole was shown to bind to purified tubulin. Immunofluorescence studies using antitubulin antibody showed that parbendazole effectively depolymerizes cytoplasmic
M Korenaga et al.
Experimental parasitology, 55(3), 358-363 (1983-06-01)
Immunogenicity of adult Strongyloides ratti was studied in rats. Immunization of rats by intraduodenal implantation of adult worms could completely inhibit the egg production and hasten the expulsion of challenged worms which were developed from subcutaneously inoculated L3 or were
D R Hennessy et al.
Journal of veterinary pharmacology and therapeutics, 15(1), 10-18 (1992-03-01)
The effect of intraruminal administration of parbendazole (PBZ) on the flow rate of bile and the pharmacokinetic behaviour of oxfendazole (OFZ) was examined in sheep. PBZ given at 18, 9 and 4.5 mg/kg resulted in a dose-related reduction in bile

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