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Merck
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重要文件

21760

Sigma-Aldrich

卡巴胆碱

purum, ≥99.0% (AT)

同義詞:

卡巴胆碱, 氯化氨甲酸胆碱, (2-羟乙基)三甲基氯化铵氨基甲酸酯

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About This Item

線性公式:
NH2COOCH2CH2N(Cl)(CH3)3
CAS號碼:
分子量::
182.65
Beilstein:
3917459
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200

等級

purum

化驗

≥99.0% (AT)

mp

200-210 °C (dec.)
210 °C (dec.) (lit.)

SMILES 字串

[Cl-].C[N+](C)(C)CCOC(N)=O

InChI

1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

InChI 密鑰

AIXAANGOTKPUOY-UHFFFAOYSA-N

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其他說明

Agonist of muscarinic acetylcholine receptors

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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分析證明 (COA)

Lot/Batch Number

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N M Nathanson et al.
The Journal of pharmacology and experimental therapeutics, 229(2), 455-458 (1984-05-01)
Previous work has demonstrated that prolonged treatment of chick embryos in vivo with muscarinic agonists leads to a decrease in the number of muscarinic acetylcholine binding sites in the heart and a decrease in the sensitivity of isolated atria to
S Uchida et al.
European journal of pharmacology, 100(3-4), 291-298 (1984-05-04)
Multiple site models of muscarinic acetylcholine receptors (mAChR) for agonist binding were applied to curves for the inhibition of QNB binding by carbachol by using nonlinear least square regression analysis. The effects of a guanine nucleotide guanyl-5'-yl imidodiphosphate (Gpp(NH)p) and
Jianmin Zhao et al.
Stem cells and development, 26(7), 528-540 (2016-12-09)
The epicardium promotes neovascularization and cardiomyocyte regeneration by generating vascular smooth muscle cells (SMCs) and producing regenerative factors after adult heart infarction. It is therefore a potential cell resource for repair of the injured heart. However, the epicardium also participates
Kalinne Kelly Lima Gadelha et al.
Experimental physiology, 104(2), 199-208 (2018-12-19)
What is the central question of this study? Is the responsiveness of isolated segments of the rat oesophagus to contractile or relaxant stimuli susceptible to acute luminal exposure of the oesophagus to an acid solution that contains pepsin and bile
Megan J Agajanian et al.
Cell reports, 26(1), 79-93 (2019-01-04)
β-Catenin-dependent WNT signal transduction governs development, tissue homeostasis, and a vast array of human diseases. Signal propagation through a WNT-Frizzled/LRP receptor complex requires proteins necessary for clathrin-mediated endocytosis (CME). Paradoxically, CME also negatively regulates WNT signaling through internalization and degradation

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