形狀
powder
powder with small lumps
比活性
≥150 U/mg protein (protein ca. 40%)
分子量
107 kDa by gel filtration
57 kDa by SDS-PAGE
運輸包裝
wet ice
儲存溫度
−20°C
InChI
1S/C7H5Cl2NO5S/c8-4-2-5(9)6(16(13,14)15-10)1-3(4)7(11)12/h1-2H,10H2,(H,11,12)
InChI 密鑰
DHUYKLYJBKXDBM-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
物理性質
牛肝脏中的蛋白质二硫键异构酶 (PDI) 是一种分子量为 107 kDa 的同源二聚体（凝胶过滤），已报告单体的分子量为 57 kDa (SDS-PAGE)。该酶是总碳水化合物含量为 12% 的糖蛋白，由 4.6% 的甘露糖、2.5% 的半乳糖、1.4% 的 NANA 和 3.5% 的 2-乙酰胺基-2-脱氧葡萄糖组成。
單位定義
1 unit corresponds to the amount of enzyme, which, in a glutathione-dithiothreitol-system, causes a change of absorbance of 0.001 per minute at pH 4.0 and 25°C.
其他說明
Enzyme that accelerates the exchange reaction between disulfide bridges in proteins
Pryank Patel et al.
Journal of molecular biology, 425(5), 929-943 (2013-01-01)
Anterior gradient 2 (AGR2) is a normal endoplasmic reticulum protein that has two important abnormal functions, amphibian limb regeneration and human cancer metastasis promotion. These normal intracellular and abnormal extracellular roles can be attributed to the multidomain structure of AGR2.
Zegbeh Z Kpadeh et al.
Journal of bacteriology, 195(8), 1825-1833 (2013-02-26)
The extracytoplasmic assembly of the Dot/Icm type IVb secretion system (T4SS) of Legionella pneumophila is dependent on correct disulfide bond (DSB) formation catalyzed by a novel and essential disulfide bond oxidoreductase DsbA2 and not by DsbA1, a second nonessential DSB
Pamela A Wearsch et al.
Methods in molecular biology (Clifton, N.J.), 960, 67-79 (2013-01-19)
The stability of the MHC (major histocompatibility complex) class I peptide repertoire is optimized during assembly in the endoplasmic reticulum (ER) and depends on the collective function of components of the peptide-loading complex (PLC). The chaperone-like molecule tapasin is the
Florian Langer et al.
Blood, 121(12), 2324-2335 (2013-01-15)
Lymphocyte depletion with antithymocyte globulin (ATG) can be complicated by systemic coagulation activation. We found that ATG activated tissue factor procoagulant activity (TF PCA) on monocytic cells more potently than other stimuli that decrypt TF, including cell disruption, TF pathway
Louise H Boyle et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(9), 3465-3470 (2013-02-13)
Tapasin is an integral component of the peptide-loading complex (PLC) important for efficient peptide loading onto MHC class I molecules. We investigated the function of the tapasin-related protein, TAPBPR. Like tapasin, TAPBPR is widely expressed, IFN-γ-inducible, and binds to MHC
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