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重要文件

02191

Sigma-Aldrich

己二酸二酰肼

purum, ≥97.0% (NT)

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About This Item

線性公式:
NH2NHCO(CH2)4CONHNH2
CAS號碼:
分子量::
174.20
Beilstein:
973863
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

等級

purum

化驗

≥97.0% (NT)

mp

180-182 °C (lit.)
180-182 °C

SMILES 字串

NNC(=O)CCCCC(=O)NN

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

InChI 密鑰

IBVAQQYNSHJXBV-UHFFFAOYSA-N

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應用

Adipic acid dihydrazide can be used to study chemical synthesis, organic building blocks, carbonyl compounds and hydrazides. Adipic acid dihydrazide has been used in a study to show that diphtheria toxoid can be successfully employed as a carrier protein for conjugation with Salmonella O-specific polysaccharides and play an important role in facilitating adequate immune response in typhoid fever vaccines. Adipic acid dihydrazide has also been used in a study to assess the activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana.

其他說明

Bifunctional linker employed for the immobilization of carbohydrates, e.g. to MMAC resins (methyl vinyl ether, maleic anhydride co-polymer)

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產品號碼
描述
訂價

象形圖

Environment

危險聲明

防範說明

危險分類

Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

302.0 °F - closed cup

閃點(°C)

150 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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A Satoh et al.
Analytical biochemistry, 275(2), 231-235 (1999-12-20)
The immobilization of carbohydrates for solid-phase assays, including enzyme-linked immunosorbent assay (ELISA), is difficult because they are hydrophilic. We developed four new methods for the immobilization of oligosaccharides. ELISA plates were first coated with methyl vinyl ether-maleic anhydride copolymer (MMAC)
A Satoh et al.
Analytical biochemistry, 260(1), 96-102 (1998-07-02)
We have previously reported a method to immobilize protein ligands on microtiter plates coated with methyl vinyl ether-maleic anhydride copolymer (MMAC) [Isosaki, K., et al. (1992) J. Chromatogr. 597, 123-128]. In this study, we improved the MMAC method to efficiently
So Jung An et al.
Vaccine, 29(44), 7618-7623 (2011-08-17)
In this study it was demonstrated that the immunogenicity of Vi polysaccharide-diphtheria toxoid conjugates was related to the physical and chemical structure of the conjugate. Conjugates were prepared in two steps, firstly binding adipic acid dihydrazide (ADH) spacer molecules to
Shuang J Yang et al.
Analytical chemistry, 84(5), 2232-2238 (2012-02-07)
Investigation into glycoproteins and their associated glycans is the key to understanding the function of glycoproteins in biological pathways and disease development. Current methods for glycan analysis are generally based on multiple preparation processes to separate glycans from proteins and
Tulsidas G Shrivastav et al.
Journal of immunoassay & immunochemistry, 24(2), 191-203 (2003-06-05)
The first step of enzyme linked immunosorbent assay (ELISA), namely, adsorption of antigen or antibody to the plastic microtiter well plate, was studied as a function of insolubility of IgG in water. Immobilization efficiency was assessed in terms of number

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