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Merck
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重要文件

02010595

缬草烯酸

primary reference standard

同義詞:

(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-六氢-3,7-二甲基-1H-茚-4-基]-2-甲基-2-丙烯酸

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About This Item

經驗公式(希爾表示法):
C15H22O2
CAS號碼:
分子量::
234.33
Beilstein:
3138020
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

primary reference standard

儲存期限

limited shelf life, expiry date on the label

製造商/商標名

HWI

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

food and beverages

SMILES 字串

[H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI

1S/C15H22O2/c1-9-4-6-12(8-11(3)15(16)17)14-10(2)5-7-13(9)14/h8-9,12-13H,4-7H2,1-3H3,(H,16,17)/b11-8+/t9-,12+,13-/m1/s1

InChI 密鑰

FEBNTWHYQKGEIQ-SUKRRCERSA-N

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一般說明

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

應用

草药产品分析的标准品。

其他說明

This compound is commonly found in plants of the genus: valeriana

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Andres Navarrete et al.
Journal of AOAC International, 89(1), 8-15 (2006-03-04)
The roots and rhizomes of various valeriana species are currently used as a sleeping aid or mild sedative. A liquid chromatography method has been developed that permits the analysis of chlorogenic acid, lignans, flavonoids, valerenic acids, and valpotrates in various
S Khom et al.
British journal of pharmacology, 161(1), 65-78 (2010-08-20)
Subunit-specific modulators of gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors can help to assess the physiological function of receptors with different subunit composition and also provide the basis for the development of new drugs. Valerenic acid (VA) was recently identified
Jürgen Ramharter et al.
Organic letters, 11(5), 1151-1153 (2009-01-31)
The first total synthesis of the sesquiterpenoid valerenic acid, a constituent of Valeriana officinalis, is described. The compound is a potent modulator of the GABA(A) receptor and may thus be useful in the treatment of various dysfunctions of the central
Chethan Sampath et al.
Planta medica, 78(6), 575-581 (2012-03-14)
Valerenic acid (VA), a sesquiterpenoid, is one of the major secondary bioactive metabolites of VALERIANA OFFICINALIS L. Until now IN VIVO studies on the absorption, bioavailability, disposition, and metabolism of VA are limited. We established and validated an LC-MS/MS assay
Takashi Kitayama et al.
Bioscience, biotechnology, and biochemistry, 74(9), 1963-1964 (2010-09-14)
A concise synthesis of valerena-4,7(11)-diene with potent sedative activity was achieved in three steps involving, reduction of carboxylic acid, bromination of the resulting alcohol, and reduction of the bromide from valerenic acid in a 63% total yield. This synthetic method

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