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Merck
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01-1350

Sigma-Aldrich

丙烯腈

SAJ first grade, ≥98.0%

同義詞:

乙烯基氰

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About This Item

線性公式:
CH2=CHCN
CAS號碼:
分子量::
53.06
Beilstein:
605310
EC號碼:
MDL號碼:
分類程式碼代碼:
12352300
PubChem物質ID:

等級

SAJ first grade

蒸汽密度

1.83 (vs air)

蒸汽壓力

86 mmHg ( 20 °C)

化驗

≥98.0%

自燃溫度

897 °F

expl. lim.

17 %

存貨情形

available only in Japan

折射率

n20/D 1.391 (lit.)

bp

77 °C (lit.)

mp

−83 °C (lit.)

SMILES 字串

C=CC#N

InChI

1S/C3H3N/c1-2-3-4/h2H,1H2

InChI 密鑰

NLHHRLWOUZZQLW-UHFFFAOYSA-N

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應用

丙烯腈可用于制造丙烯酸纤维、树脂(丙烯腈-丁二烯-苯乙烯、苯乙烯-丙烯腈等)以及丁腈橡胶(丁二烯-丙烯腈)。

生化/生理作用

属工业致癌物,对大鼠具有多位点致癌性,也可能对人体具有致癌性。

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

23.0 °F - closed cup

閃點(°C)

-5 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


分析證明 (COA)

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J Whysner et al.
Regulatory toxicology and pharmacology : RTP, 27(3), 217-239 (1998-08-07)
Acrylonitrile (ACN) exposure is associated with tumors in rat brain, Zymbal gland, and mammary gland. Adducts affecting base pairing were formed in isolated DNA exposed in vitro to the ACN metabolite cyanoethylene oxide (CNEO). DNA from liver, which is not
A Léonard et al.
Mutation research, 436(3), 263-283 (1999-06-04)
Acrylonitrile (AN) is an important intermediary for the synthesis of a variety of organic products, such as artificial fibres, household articles and resins. Although acute effects are the primary concern for an exposure to AN, potential genotoxic, carcinogenic and teratogenic
Acrylonitrile and human cancer--an overview.
D Coggon et al.
Scandinavian journal of work, environment & health, 24 Suppl 2, 81-82 (1998-08-26)
Philip Cole et al.
Regulatory toxicology and pharmacology : RTP, 52(3), 342-351 (2008-10-18)
Several retrospective cohort epidemiology studies evaluated a number of health outcomes in workers exposed to acrylonitrile (AN). The epidemiology studies included in this review have been published since 1970 and were identified through Ovid and MEDLINE retrieval services using search
Takeo Suzuki et al.
Nucleic acids research, 42(11), 7346-7357 (2014-05-17)
In mammalian mitochondria, 22 species of tRNAs encoded in mitochondrial DNA play crucial roles in the translation of 13 essential subunits of the respiratory chain complexes involved in oxidative phosphorylation. Following transcription, mitochondrial tRNAs are modified by nuclear-encoded tRNA-modifying enzymes.

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