SCC717

3dGRO^® Pancreatic Organoids (OCIP.180)

• 同義詞: organoid, PDO, cancer organoid, tumor organoid, 3d cell culture, pancreatic cancer, PDCAC organoid, cancer, organoid cell line
• 分類程式碼代碼: 41106514
• NACRES: NA.7

屬性

• 生物源: human
• 品質等級: 100
• 包裝: vial of ≥1500 organoids/vial vials
• 製造商／商標名: Millipore
• 技術: cell culture | mammalian: suitable; cell culture | stem cell: suitable
• 運輸包裝: liquid nitrogen
• 儲存溫度: −196°C

描述

一般說明

The pancreas is both an endocrine and exocrine organ that plays role in digestion and metabolic homeostasis. Endocrine compartments include the alpha and beta cells which secrete the hormones glucagon and insulin and exocrine compartment including acinar cells, which store and secrete digestive enzymes and highly branched, tubular epithelial tree–like ductal networks. Pancreatic ductal adenocarcinoma (PDACs) is one of the most lethal forms of cancer with 5-year survival rates less than 8% and is projected to be the second most common cause of cancer-related deaths by 2030.

Recent breakthroughs in three-dimensional (3D) culture methods have led to the development of organoid culture platforms, which allow researchers to perform translational research on long-term in vitro cultures not limited by barriers present in 2D culture or animal models. We now offer a comprehensive collection of patient derived pancreatic ductal adenocarcinoma cancer (PDAC) organoids for cancer research and drug discovery applications.

Cell Line Characteristics

• Sex: Male
• Age: 64 Years
• Organ: Pancreas (Xenograph from Primary Tumor)
• Disease: Ductal Adenocarcinoma (KRAS mutation: Wild-type)

應用

• Viability: >=1500 viable organoids/vial
• Organoid Growth: Pass
• Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Mycoplasma Contamination: Negative
• STR Profile: Pass

特點和優勢

Cryopreserved patient derived pancreatic cancer organoids (PDOs)

儲存和穩定性

Store in liquid nitrogen. The organoids can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

法律資訊

3dGRO is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable