Pellicon® 3 cassettes with Biomax membrane are the optimum tangential flow filtration (TFF) devices for the filtration of solutions containing therapeutical proteins, albumin, hormones, vaccines and growth factors. These advanced, high-performance cassettes are ideal for today’s higher titer therapeutic antibodies, higher viscosity feed formulations as well as the more demanding filtration processes that require higher operating pressures, temperatures and caustic cleaning regimes.From small-scale to full-scale production, Pellicon® 3 cassettes are designed for use in research, process scale-up/scale-down, applications development and full-scale manufacturing. The Pellicon® 3 design and automated manufacturing process provides unbeatable performance consistency between cassette sizes. Pellicon® 3 devices also offer greater cassette size selection for improved scale-up and scale-down process development. The streamlined design allows operators to quickly and easily handle, install and remove Pellicon® 3 cassettes. The materials of construction are compatible with a broad range of chemical cleaning.
應用
monoclonal antibodies, recombinant and non-recombinant proteins, vaccines
特點和優勢
Robust, void-free membrane provides optimum productretention and performance consistency
Unique feed screen design enables high mass transfer, flux for higher finalconcentration
Fast, reliable scale up/down from lab to production scale
