MABN450

Anti-GCM2 Antibody, clone 8A10.1

clone 8A10.1, 0.5 mg/mL, from mouse

• 同義詞: hGCMb, Chorion-specific transcription factor GCMb, GCM2, GCM 2, GCM-2, GCM motif protein 2, Glial cells missing homolog 2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 8A10.1, monoclonal
• 物種活性: human
• 濃度: 0.5 mg/mL
• 技術: western blot: suitable
• 同型: IgMκ
• NCBI登錄號: NP_004743
• UniProt登錄號: O75603
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GCM2(9247)

描述

一般說明

GCM2 is a nuclear protein that is involved in transcription regulation of many genes including ones important in parathyroid metabolism and development. Glial cells missing homolog 2 or GCM2 is expressed predominately in the pharyngeal pouches and, at later stages, in the developing and mature parathyroid glands. In humans, loss of GCM2 function, either through recessive apomorphic mutations or dominant inhibitor mutations in the human GCM2 gene, leads to isolated hypoparathyroidism. GCM2 expression is continued in the adult parathyroid at high levels and appears to be important in calcium sensing and calcium receptor expression in adult parathyroid cells.

免疫原

GST-tagged recombinant protein corresponding to Human GCM2.

應用

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

This Anti-GCM2 Antibody, clone 8A10.1 is validated for use in Western Blotting for the detection of GCM2.

品質

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected GCM2 in 10 µg of SH-SY5Y cell lysate.

標靶描述

~ 58 kDa observed. An uncharacterized band appears at ~110 kDa in some lysates.

外觀

Format: Purified

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2