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Merck
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Key Documents

MABN250

Sigma-Aldrich

Anti-RA-induced protein 17 Antibody, clone 5H5.1

clone 5H5.1, from mouse

同義詞:

Retinoic acid-induced protein 17, ZMIZ1, Zinc finger MIZ domain-containing protein 1, PIAS-like protein Zimp10

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

5H5.1, monoclonal

物種活性

human

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ZMIZ1(57178)

一般說明

Retinoic acid-induced protein 17 (RAI17) is also called Zinc finger MIZ domain-containing protein 1 (ZMIZ1), and PIAS-like protein Zimp10. Retinoic acid-induced protein 17 promotes AR sumoylation and increases AR ligand-dependent transcriptional activity. Retinoic acid-induced protein 17 is highly expressed in ovary and at lower levels in prostate, spleen and testis.

免疫原

Recombinant protein corresponding to human RA-induced protein 17.

應用

Detect Retinoic acid-induced protein 17 using this mouse monoclonal antibody, Anti-RA-induced protein 17 Antibody, clone 5H5.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RA-induced protein 17 in human thalamus tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected RA-induced protein 17 in 10 µg of SH-SY5Y cell lysate.

標靶描述

~115 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing at ~115 kDa and ~107 kDa

外觀

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Sameer Aryal et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(18) (2021-04-29)
Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, but its translational targets and modes of control remain in dispute. We previously showed that genetic removal of

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