MABF1497
Anti- CD161 (NK1.1) (mouse), redFluor® 710, clone PK136 Antibody
clone PK136, from mouse, redFluor® 710
同義詞:
Killer cell lectin-like receptor subfamily B member 1B allele A, CD161 antigen-like family member B, Lymphocyte antigen 55b (Ly-55b), NKR-P1 34, Natural killer cell surface protein NKR-P1B allele SJL/BALB (NKR-P1B), CD161b, CD161 (NK1.1)
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About This Item
生物源
mouse
品質等級
共軛
redFluor® 710
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
PK136, monoclonal
物種活性
mouse
技術
flow cytometry: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Klrb1C(17059)
相關類別
一般說明
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
Anti- CD161 (NK1.1) (mouse), redFluor® 710, clone PK136 Antibody is an antibody against CD161 for use in Flow Cytometry.
品質
This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD161 (NK1.1) in one million C57Bl/6 splenocytes.
Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD161 (NK1.1) in one million C57Bl/6 splenocytes.
其他說明
Concentration: Please refer to lot specific datasheet.
法律資訊
redFluor is a registered trademark of Tonbo Biotechnologies
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
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