MABC713

Anti-KEAP1, clone 7G4B10 Antibody

clone 7G4B10, from mouse

• 同義詞: Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 無性繁殖: 7G4B10, monoclonal
• application: ELISA; FACS; IHC
• 物種活性: human
• 技術: ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 7G4B10, monoclonal
• 物種活性: human
• 技術: ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable
• UniProt登錄號: Q14145
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KEAP1(9817)

描述

一般說明

Kelch-like ECH-associated protein 1, also known as Cytosolic inhibitor of Nrf2 or INrf2 or Kelch-like protein 19, and encoded by the gene name KEAP1 or INRF2 or KLHL19, acts as a substrate adapter protein for the E3 ubiquitin ligase complex and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 shuttles between the cytoplasm and the nucleus and is widely expressed with high levels found in skeletal muscle.

免疫原

Purified recombinant fragment of human KEAP1 expressed in E. Coli

應用

Anti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.

Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected KEAP1 in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

品質

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KEAP1 in bladder cancer and cerebellum tissues.

標靶描述

70 kDa calculated

外觀

Protein G Purified

Format: Purified

Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable