MABC293

Anti-NLRP10 Antibody, clone 8H2

clone 8H2, from rat

• 同義詞: NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rat
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 8H2, monoclonal
• 物種活性: human
• 技術: flow cytometry: suitable; immunocytochemistry: suitable; western blot: suitable
• 同型: IgG2aκ
• NCBI登錄號: NP_789791
• UniProt登錄號: Q86W26
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NLRP10(338322)

描述

一般說明

NACHT, LRR and PYD domains-containing protein 10 (NLRP10) is also called Nucleotide-binding oligomerization domain protein 8. NLRP10 has anti-inflammatory activity and plays a role in immune response against infections from bacteria including C.albicans by contributing to proinflammatory cytokine release. NLRP10 is widely expressed with the highest levels found in heart, brain and skeletal muscle, as well as liver, colon, dermis and epidermis.

免疫原

Recombinant protein corresponding to human NLRP10.

應用

Anti-NLRP10 Antibody, clone 8H2 is a highly specific rat monoclonal antibody, that targets NLRP10 & has been tested in western blotting, Flow Cytometry & ICC.

Immunocytochemistry Analysis: A representative lot from an independent laboratory detected NLRP10 in Flag-tagged NRLP10 transfected HeLa cells (Lautz, K., et al. (2012). Cell Microbiol. 14(10:1568-1583.).

Western Blotting Analysis: A representative lot from an independent laboratory detected NLRP10 primary epidermal fibroblasts transfected with a non-targeting control siRNA, and demonstrated a loss of signal in primary epidermal fibroblasts transfected with NLRP10-specific RNA (Lautz, K., et al. (2012). Cell Microbiol. 14(10:1568-1583.).

Flow Cytometry Analysis: 4 µg from a representative lot detected NLRP10 in 1X10E6 HeLa and Jurkat cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

品質

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 1 mg/mL of this antibody detected NLRP10 in 10 µg of A431 cell lysate.

標靶描述

~72 kDa observed

外觀

Protein G Purified

Format: Purified

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
A431 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable