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MAB5550

Sigma-Aldrich

Anti-TorsinA Antibody

ascites fluid, Chemicon®

同義詞:

Anti-AMC5, Anti-DYT1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

monoclonal

物種活性

mouse, rat, human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TOR1B(27348)

一般說明

TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.

特異性

TorsinA

免疫原

Maltose binding protein fusion protein from human torsinA.

應用

Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neurodegenerative Diseases
This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.

標靶描述

37kDa

外觀

Ascites
Liquid. Contaings no preservative

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

分析報告

Control
Positive Control: Human brain lysate, NGF treated PC12 cells.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Diminishing evidence for torsinA-positive neuronal inclusions in DYT1 dystonia.
Drew Pratt et al.
Acta neuropathologica communications, 4(1), 85-85 (2016-08-18)

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