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重要文件

MAB443

Sigma-Aldrich

Anti-Estrogen Receptor Antibody, clone AER304

ascites fluid, clone AER304, Chemicon®

同義詞:

ER

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

AER304, monoclonal

物種活性

bovine, human, chicken, mouse

製造商/商標名

Chemicon®

技術

electrophoretic mobility shift assay: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ESR1(2099)

特異性

Estrogen receptor 67kD hormone binding subunit. Epitope localized between aa 120-170.

免疫原

Bovine estrogen receptor.
Epitope: a.a. 120-170

應用

Anti-Estrogen Receptor Antibody, clone AER304 is a Mouse Monoclonal Antibody for detection of Estrogen Receptor also known as ER & has been validated in EMSA, IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Western blot (human)

Immunoprecipitation (human)

Immunohistochemistry (mouse)

Optimal working dilutions must be determined by the end user.

聯結

Replaces: 04-227

外觀

Liquid

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Shyam Nathan et al.
Breast cancer research and treatment, 166(3), 681-693 (2017-08-16)
We previously identified small molecules that fit into a BRCA1-binding pocket within estrogen receptor-alpha (ERα), mimic the ability of BRCA1 to inhibit ERα activity ("BRCA1-mimetics"), and overcome antiestrogen resistance. One such compound, the hydrochloride salt of NSC35446 ("NSC35446.HCl"), also inhibited

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