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MAB1950

Sigma-Aldrich

Anti-Integrin α2 Antibody, clone P1E6

clone P1E6, Chemicon®, from mouse

同義詞:

CD49b

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

P1E6, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable

同型

IgG1

適合性

not suitable for immunohistochemistry (Paraffin)

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ITGA2(3673)

特異性

Reacts with Human a2 integrin.

應用

Anti-Integrin α2 Antibody, clone P1E6 is an antibody against Integrin α2 for use in IC, IH.
Research Category
Cell Structure
Research Sub Category
Integrins
Suitable for use in attachment inhibition assays using fibroblasts, epithelial cells, endothelial cells, and non-activated platelets on collagen types I, III, IV, VI and laminin.

Suitable for immunofluorescence using fresh frozen or acetone fixed tissues. Not recommended for traditional formalin fixed paraffin embedded tissues.

Final working dilutions must be determined by end user.

外觀

Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 0.01 M phosphate buffered saline, pH 7.1, with 0.1% sodium azide as a preservative.

儲存和穩定性

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
Skin (Basement membrane)

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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P D Arora et al.
The American journal of pathology, 154(3), 871-882 (1999-03-18)
Wound contraction is mediated by myofibroblasts, specialized fibroblasts that appear in large numbers as the wound matures and when resistance to contractile forces increases. We considered that the regulation of myofibroblast differentiation by wound-healing cytokines may be dependent on the
P Sriramarao et al.
Endothelium : journal of endothelial cell research, 4(2), 85-97 (1996-01-01)
A direct correlation was observed between the invasive and metastatic potential of A375 melanoma cells and their expression of tenascin and ability to support endothelial cell adhesion and reorganization. Since the ability to metastasize and establish a neovasculature requires interaction
Hirokazu Date et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 28(2), 225-231 (2009-09-03)
Cellular activities responding to growth factors are important in ligament healing. The anterior cruciate ligament (ACL) has poor healing potential compared to the medial collateral ligament (MCL). To assess the differences, we investigated the proliferation, migration, adhesion, and matrix synthesis
B K Pilcher et al.
The Journal of cell biology, 137(6), 1445-1457 (1997-06-16)
We have shown in a variety of human wounds that collagenase-1 (MMP-1), a matrix metalloproteinase that cleaves fibrillar type I collagen, is invariably expressed by basal keratinocytes migrating across the dermal matrix. Furthermore, we have demonstrated that MMP-1 expression is
Tao Wang et al.
Blood, 105(7), 2836-2844 (2004-12-04)
CD97, a membrane protein expressed at high levels on inflammatory cells and some carcinomas, is a member of the adhesion G protein-coupled receptor family, whose members have bipartite structures consisting of an extracellular peptide containing adhesion motifs noncovalently coupled to

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