推薦產品
一般說明
抗CDH1(Ab-2),小鼠单克隆,克隆DH01,可识别大鼠1细胞中约55 kDa Cdh-1蛋白。它已被验证可用于蛋白质印迹和免疫沉淀。
用指定的免疫原免疫BALB/c小鼠,并将脾细胞与Sp2/0小鼠骨髓瘤融合而产生的纯化的小鼠单克隆抗体。识别约为55 kDa的ID1蛋白。
识别大鼠1细胞中~55 kDa Cdh-1蛋白。
免疫原
人
重组人Cdh1蛋白
應用
免疫印迹(1 g/mL)
免疫沉淀(2 g/mg蛋白裂解物)
包裝
请参考特定浓度批号的标签。
警告
毒性:标准处理(A)
外觀
在10 mM PBS,0.2%BSA,pH值7.4中。
分析報告
阳性对照
:KAT或LS174T细胞
:KAT或LS174T细胞
阴性对照
正常小鼠血清
正常小鼠血清
其他說明
Kramer, E.R., et al. 2000 Mol.Biol. Cell11, 1555.
Petersen, B.O., et al. 2000 Genes Dev.14, 2330.
Pfleger, C.M., et al. 2001 Genes Dev.15, 1759.
Sorensen, C.S., et al. 2001 Mol.Cell Biol.21, 3692.
Gieffers, C., et al. 1999 Proc.Natl.Acad.Sci. USA96, 11317.
Visintin, R., et al. 1997 Science278, 460.
Petersen, B.O., et al. 2000 Genes Dev.14, 2330.
Pfleger, C.M., et al. 2001 Genes Dev.15, 1759.
Sorensen, C.S., et al. 2001 Mol.Cell Biol.21, 3692.
Gieffers, C., et al. 1999 Proc.Natl.Acad.Sci. USA96, 11317.
Visintin, R., et al. 1997 Science278, 460.
不与其他含有WD重复序列的蛋白质(包括Cdc20)发生交叉反应。在单个系统中,应对抗体进行滴定以获得最佳结果。
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
The EMBO journal, 25(8), 1741-1752 (2006-04-08)
The human T-lymphotropic virus type 1 (HTLV-1) Tax binds the anaphase promoting complex (APC) and activates it ahead of schedule. Here, we show that APC activation by Tax induces rapid senescence (tax-IRS) independently of p53 and pRB. In response to
Cell cycle (Georgetown, Tex.), 15(7), 931-947 (2016-03-11)
We previously reported that aberrant TGF-β/Smad2/3 signaling in endometrial cancer (ECA) leads to continuous ubiquitylation of p27(kip1)(p27) by the E3 ligase SCF-Skp2/Cks1 causing its degradation, as a putative mechanism involved in the pathogenesis of this cancer. In contrast, normal intact
Oncogene, 30(1), 21-31 (2010-08-31)
Inactivation of von Hippel-Lindau tumor-suppressor protein (pVHL) is associated with von Hippel-Lindau disease, an inherited cancer syndrome, as well as the majority of patients with sporadic clear cell renal cell carcinoma (RCC). Although the involvement of pVHL in oxygen sensing
Cell death & disease, 11(4), 298-298 (2020-04-30)
APC/CCdh1 is a ubiquitin ligase with roles in numerous diverse processes, including control of cellular proliferation and multiple aspects of the DNA damage response. Precise regulation of APC/CCdh1 activity is central to efficient cell-cycle progression and cellular homeostasis. Here, we
Molecular biology of the cell, 31(6), 419-438 (2020-01-23)
Chromosome segregation during mitosis is antagonistically regulated by the Aurora-B kinase and RepoMan (recruits PP1 onto mitotic chromatin at anaphase)-associated phosphatases PP1/PP2A. Aurora B is overexpressed in many cancers but, surprisingly, this only rarely causes lethal aneuploidy. Here we show
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