ABT410

Anti-MATN3 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Matrilin-3
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse
• 技術: immunocytochemistry: suitable; western blot: suitable
• UniProt登錄號: O15232
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Matn3(17182)

描述

一般說明

Matrilin-3 (MATN3) is a major component of the extracellular matrix of cartilage. MATNs are a family of non-collagenous extracellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

免疫原

KLH-conjugated synthetic peptide corresponding to the C-terminus of human MATN3.

應用

Detect MATN3 using this Anti-MATN3 Antibody validated for use in western blotting & ICC.

Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected MATN3 in NIH/3T3 cells.

品質

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected MATN3 in NIH/3T3 cell lysate.

標靶描述

~52 kDa observed. Uncharacterized bands may be observed in some lysate(s).

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable