ABT405

Anti-KIF5 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC, KIF5A
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• UniProt登錄號: Q12840
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KIF5A(3798)

描述

一般說明

Kinesin heavy chain isoform 5A, also known as Kinesin heavy chain neuron-specific 1 or Neuronal kinesin heavy chain (NKHC), and encoded by the gene name KIF5A or NKHC1, are members of the kinesin superfamily of proteins (KIFs). These proteins are microtubuledependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; KIF5A (117 kDa), KIF5B (39 kDa), and KIF5C (39 kDa). Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias

特異性

This antibody recognizes all isoforms of KIF5.

免疫原

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human KIF5.

應用

Anti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence.

Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected KIF5 in K562 cells.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

品質

Evaluated by Western Blotting in K562 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.

標靶描述

~116 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外觀

Affinity

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable