跳轉至內容
Merck
全部照片(1)

重要文件

ABN160

Sigma-Aldrich

Anti-ARMS2 Antibody

from rabbit, purified by affinity chromatography

同義詞:

Age-related maculopathy susceptibility protein 2

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ARMS2(387715)

一般說明

Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly.

免疫原

KLH-conjugated linear peptide corresponding to human ARMS2.

應用

Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in ARPE-19 cells. (Pericak-Vance, M., et al. (2009). Invest Ophthalmol Vis Sci. 50(7): 3084–3090.)
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
This Anti-ARMS2 Antibody is validated for use in Western Blotting for the detection of ARMS2.

品質

Evaluated by Western Blot in human placenta tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ARMS2 on 10 µg of human placenta tissue lysate.

標靶描述

~12 kDa observed. An uncharacterized band appears at ~60 kDa in some lysates.

外觀

Affinity purified
Purified rabbit polyclonal in PBS containing 0.1% azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human placenta tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到適合的產品?  

試用我們的產品選擇工具.

儲存類別代碼

10 - Combustible liquids


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Mao Nakayama et al.
Investigative ophthalmology & visual science, 55(10), 6514-6523 (2014-09-11)
We determined the function of ARMS2 and HtrA1 in the choroid and retina using transgenic (Tg) mice and evaluated the effects of mainstream cigarette smoke on these mice. The chicken actin promoter (CAG) was used to drive mouse HtrA1, human

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務