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Key Documents

AB5050P

Sigma-Aldrich

Anti-NMDAR1 Splice Variant C2 Antibody

Chemicon®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat, mouse

包裝

antibody small pack of 25 μg

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Grin1(14810)
rat ... Grin1(24408)

相關類別

特異性

Specific for the NMDAR1 containing the C2′ splice variant insert. The antibody does not recognize the NMDAR1 subunits of the NMDA receptor that do not contain the C2′ insert. By Western blot the antibody recognizes a protein with molecular weight of 120 kDa. Also labels a single higher molecular weight band that may be a posttranslationally modified form of the protein.

免疫原

Peptide corresponding to the C-terminus of the rat NMDAR1 C2′ splice variant.

應用

Detect NMDAR1 Splice Variant C2 using this Anti-NMDAR1 Splice Variant C2 Antibody validated for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:2000 using ECL

Immunohistochemistry: 1:1000

Optimal working dilutions must be determined by the end user.

外觀

Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM) so some residual salt may also be present. Reconstitute with 50 μL of PBS. Contains no preservatives.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.
McGuier, NS; Padula, AE; Lopez, MF; Woodward, JJ; Mulholland, PJ
Alcohol null
Intrauterine growth restriction due to uteroplacental insufficiency decreased white matter and altered NMDAR subunit composition in juvenile rat hippocampi.
Schober, ME; McKnight, RA; Yu, X; Callaway, CW; Ke, X; Lane, RH
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
Thorsten Pauly et al.
PloS one, 3(7), e2681-e2681 (2008-07-17)
Functional and structural alterations of clustered postsynaptic ligand gated ion channels in neuronal cells are thought to contribute to synaptic plasticity and memory formation in the human brain. Here, we describe a novel molecular mechanism for structural alterations of NR1

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