AB3749

Anti-mGCM1 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: GCM motif protein 1, Glial cells missing homolog 1, chorion-specific transcription factor GCMa, glial cells missing homolog a
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: western blot: suitable
• 輸入: sample type pancreatic stem cell(s); sample type neural stem cell(s)
• UniProt登錄號: P70348
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GCM1(8521)

描述

一般說明

GCM1 is a DNA binding protein with a GCM motif (glial cell missing motif) that is a key transcription factor for determining the fate of stem cells within the nervous system, in addition to being critical for placental development. This protein binds to the GCM motif (A/G)CCCGCAT, a novel sequence among known targets of DNA binding proteins. The N-terminal DNA-binding domain confers the unique DNA binding activity of this protein. Current studies indicate that the introduction of the mouse GCM1 gene in cultured cells from embryonic brains resulted in the induction of an astrocyte lineage.

特異性

Comparison of sequence homology suggests that this antibody will also react in mouse and rat; however, reactivity to other species has not been tested.

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from the C-terminal region mouse GCM1.

免疫原

Epitope: C-terminus

Synthetic GCM1 peptide, a.a. 401-418.

應用

Research Category
Stem Cell Research

Research Sub Category
Neural Stem Cells

This Anti-mGCM1 Antibody is validated for use in WB for the detection of mGCM1.

品質

Routinely evaluated by western blot on HEK-293 lysates.

Western Blotting: Recommended working dilutions are 1:1000 – 1:2500.

標靶描述

50 kDa

外觀

Peptide affinity purified

Purified rabbit polyclonal antibody in buffer containing PBS with 0.09% sodium azide.

儲存和穩定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable