AB2232

Anti-Atrial Natriuretic Polypetide Antibody, alpha

from rabbit

• 同義詞: Atrial natriuretic peptide, natriuretic peptide precursor A, natriuretic peptide precursor A variant 2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, mouse, human
• 技術: western blot: suitable
• NCBI登錄號: NP_006163.1
• UniProt登錄號: P01160
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NPPA(4878)

描述

一般說明

Atrial natriuretic polypeptide, alpha (ANP), atrial natriuretic factor (ANF), or atriopeptin, is a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the homeostatic control of body water, sodium, potassium and fat (adiposity). It is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes), in response to high blood pressure. ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP binds to a specific set of receptors - ANP receptors. Receptor-agonist binding causes a reduction in blood volume and therefore a reduction in cardiac output and systemic blood pressure. Lipolysis is increased and renal sodium reabsorption is decreased. The overall effect of ANP on the body is to counter increases in blood pressure and volume caused by the renin-angiotensin system (1).

特異性

Cat. # AB2232 recognizes ANP, alpha

May react with dog, cat and cow based on sequence homology.

免疫原

Synthetic Linear Peptide

應用

Non-Lot Specific Tested Application 1:
Immunohistochemistry:
1:50-1:500 on paraffin embedded tissue.

Optimum dilutions need to be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Neurotransmitters & Receptors

This Anti-Atrial Natriuretic Polypetide Antibody, alpha is validated for use in WB for the detection of Atrial Natriuretic Polypetide.

品質

Routinely evaluated by western blot

標靶描述

~17 kDa

外觀

Purified

Format: Purified

Purified in 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.

分析報告

Control
Rat Heart

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable