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8.52046-M

Sigma-Aldrich

Fmoc-Ser(Trt)-OH

Novabiochem®

同義詞:

Fmoc-Ser(Trt)-OH, N-α-Fmoc-O-trityl-L-serine

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About This Item

經驗公式(希爾表示法):
C37H31NO5
CAS號碼:
分子量::
569.65
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.22

品質等級

化驗

≥95.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

mp

200 °C

應用

peptide synthesis

官能基

hydroxyl

儲存溫度

15-25°C

InChI

1S/C37H31NO5/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1

InChI 密鑰

UCARTONYOJORBQ-UMSFTDKQSA-N

一般說明

The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS [1, 2] or 20% dichloroacetic acid in DCM [3], enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphoserine containing peptides and peptides modified at the serine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2, 4].

The product number for this product was previously 04-12-1092.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

聯結

Replaces: 04-12-1092

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(157A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Enantiomeric purity: ≥ 99.5 % (a/a)
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 2.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

Novabiochem® 提供正交保護的氨基酸用於多肽合成,包括環肽和支鏈肽。

Novabiochem® offers orthogonally protected amino acids for peptide synthesis, including cyclic and branched peptides.

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