5.05894

CGP 7930

• 同義詞: CGP 7930, GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930
• 經驗公式（希爾表示法）: C₁₉H₃₂O₂
• CAS號碼: 57717-80-3
• 分子量：: 292.46
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: pale yellow
• 溶解度: DMSO: 100 mM; ethanol: 100 mM
• 儲存溫度: 2-8°C
• InChI: 1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3
• InChI 密鑰: XLWJPQQFJNGUPA-UHFFFAOYSA-N

描述

一般說明

A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABA_B receptor. Shown to modulate GABA_B receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABA_B receptors. Exhibits anxiolytic effects in rodents.

警告

Toxicity: Standard Handling (A)

其他說明

Adams, C. et al., 2007. CNS Drug Rev.13, 308.
Pin, J.P., et al., 2007. Curr. Neuropharmacol.5, 195.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable