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Merck
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444217

Sigma-Aldrich

MMP-3, Catalytic Domain, Human, Recombinant, E. coli

同義詞:

Matrix Metalloproteinase 3, Stromelysin-1, Catalytic Domain

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About This Item

酶委員會編號:
分類程式碼代碼:
12352202
NACRES:
NA.77

化驗

≥90% (SDS-PAGE)

品質等級

形狀

liquid

比活性

≥1250 mU/mg protein

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

異物活動

other MMP activity, none detected

運輸包裝

wet ice

儲存溫度

−70°C

一般說明

Note: 1 mU = 1 milliunit.
Recombinant, human MMP-3 catalytic domain expressed in E. coli.

警告

Toxicity: Standard Handling (A)

單位定義

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol MCA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH₂ per min at 37°C, pH 7.0.

外觀

In 50 mM Tris-HCl, 10 mM CaCl₂, 1 µM ZnCl₂, 0.05% NaN₃, pH 7.5.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Nagase, H., et al. 1994. J. Biol. Chem. 269, 20952.
Wilhelm, S.M., et al. 1993. J. Biol. Chem. 268, 21906.
Ye, Q.Z., et al. 1992. Biochemistry 31, 11231.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Lise Boon et al.
The FEBS journal, 286(5), 930-945 (2018-11-14)
Matrix metalloproteinases (MMPs) are secreted as proenzymes, containing propeptides that interact with the catalytic zinc, thereby controlling MMP activation. The MMP-9 propeptide is unique in the MMP family because of its post-translational modification with an N-linked oligosaccharide. ProMMP-9 activation by

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