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重要文件

36-009

Sigma-Aldrich

Anti-β-Synuclein (SNCB) Antibody

UPSTATE®, mouse monoclonal, Syn207

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

產品名稱

Anti-β-Synuclein Antibody, clone Syn207, ascites fluid, clone Syn207, Upstate®

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

Syn207, monoclonal

物種活性

rat, mouse, human

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... SNCB(6620)

特異性

recombinant β-Synuclein

免疫原

full length recombinant human β-Synuclein

應用

Anti-β-Synuclein Antibody, clone Syn207 is an antibody against β-Synuclein for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

品質

routinely evaluated by immunoblot lot detected β-Synuclein recombinant protein

標靶描述

~17kDa

外觀

Ascites
ascites with 0.05% sodium azide

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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P H Tu et al.
Annals of neurology, 44(3), 415-422 (1998-09-28)
Recently, alpha-synuclein was shown to be a structural component of the filaments in Lewy bodies (LBs) of Parkinson's disease (PD), dementia with LBs (DLB) as well as the LB variant of Alzheimer's disease, and this suggests that alpha-synuclein could play
Emmy H Rannikko et al.
BMC neuroscience, 16, 57-57 (2015-09-09)
The pathological hallmarks of Parkinson's disease are intracellular inclusions composed mainly of misfolded α-synuclein (αSYN). Under physiological conditions αSYN is mostly localized in synapses. In addition, a portion of αSYN is secreted to the extracellular space, where it may be
B I Giasson et al.
Journal of neuroscience research, 59(4), 528-533 (2000-02-19)
To facilitate studies of the normal biology of alpha-synuclein, a member of a family of neuronal proteins of unknown function, and to elucidate the role of alpha-synuclein pathologies in neurodegenerative diseases, we generated and characterized a panel of anti-synuclein antibodies.
Development of new treatments for Parkinson's disease in transgenic animal models: a role for beta-synuclein.
Masliah, Eliezer and Hashimoto, Makoto
Neurotoxicology, 23, 461-468 (2002)
O Akil et al.
Journal of the Association for Research in Otolaryngology : JARO, 9(4), 452-463 (2008-07-31)
Synucleins are widely expressed synaptic proteins within the central nervous system that have been implicated in such neurodegenerative disorders as Parkinson's disease. In this study, an initial characterization of all three synucleins, alpha-, beta-, and gamma-synuclein, within the cochlea was

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