物種活性
human, mouse
製造商／商標名
HTRF®
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
檢測方法
fluorometric (HTRF)
運輸包裝
dry ice
應用
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Oncology
Oncology
The PIP4 Kinase HTRF Assay kit provides a method for assaying PI(5)P-4 kinases in a homogenous 1920 well format. Suitable for screening of potential inhibitors of these enzymes.
Used to detect/quantify: PIP4 Kinase
生化／生理作用
Target Sub-Family: PI3K/PI4K
包裝
Kit capacity: 1920 wells
成分
Reaction Buffer (4X)
DM A Detection Reagent
DM C Detection Reagent
DM E Detection Reagent
Phosphatidylinositol 5-phosphate (1mM)
Phosphatidylserine (1mM)
Stop Reagent D
DM A Detection Reagent
DM C Detection Reagent
DM E Detection Reagent
Phosphatidylinositol 5-phosphate (1mM)
Phosphatidylserine (1mM)
Stop Reagent D
儲存和穩定性
12 months at -70°C
法律資訊
HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
儲存類別代碼
10-13 - German Storage Class 10 to 13
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Lars Wortmann et al.
Journal of medicinal chemistry, 64(21), 15883-15911 (2021-10-27)
PIP4K2A is an insufficiently studied type II lipid kinase that catalyzes the conversion of phosphatidylinositol-5-phosphate (PI5P) into phosphatidylinositol 4,5-bisphosphate (PI4,5P2). The involvement of PIP4K2A/B in cancer has been suggested, particularly in the context of p53 mutant/null tumors. PIP4K2A/B depletion has
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