推薦產品
重組細胞
expressed in E. coli
品質等級
化驗
≥95% (SDS-PAGE)
形狀
liquid
比活性
≥900 mU/mg protein
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
avoid repeated freeze/thaw cycles
運輸包裝
wet ice
儲存溫度
−70°C
一般說明
注意:1 mU = 1百万单元。
组织蛋白酶K是半胱氨酸蛋白酶木瓜蛋白酶超家族的成员,在破骨细胞介导的骨吸收和胶原降解中起重要作用。它主要由破骨细胞表达。最近报道也在成纤维细胞中表达。活性异常会导致骨质减少性疾病,例如骨质疏松症症和致密性成骨不全症症。包含C-端His•Tag。
组织蛋白酶K是半胱氨酸蛋白酶木瓜蛋白酶超家族的成员,在破骨细胞介导的骨吸收和胶原降解中起重要作用。它主要由破骨细胞表达,最近的研究也表明它在成纤维细胞中表达。组织蛋白酶K活性异常,无论是太高还是太低,都会导致骨质减少性疾病,例如骨质疏松症症和致密性成骨不全症症。该重组酶包含C端His•Tag序列。
包裝
请参考特定浓度批号的标签。
警告
毒性:标准处理(A)
單位定義
一个单位定义为在37°C,pH 5.5下,每分钟水解0.4 µmol Z-FR-AMC的酶量。
外觀
在50 mM NaOAC,pH 5.5中。通过添加10 mM MMTS停止激活,可以在还原条件下将其去除。
重構
初次解冻后,分装冻存(-70°C)。
其他說明
Delaisse, J.M., et al. 2003.Microsc.Res. Tech.61, 504.
Dodds, R.A.2003.Cell Biochem.Funct.21, 231.
Everts, V., et al. 2003.Calcif.Tissue Int.73, 380.
Hou, W.S., et al. 2003.Biol. Chem.384, 891.
Dodds, R.A.2003.Cell Biochem.Funct.21, 231.
Everts, V., et al. 2003.Calcif.Tissue Int.73, 380.
Hou, W.S., et al. 2003.Biol. Chem.384, 891.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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