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07-502-I

Sigma-Aldrich

Anti-p67-phox (not Human) Antibody

from rabbit, purified by affinity chromatography

同義詞:

Neutrophil cytosol factor 2, NCF-2, 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, Neutrophil NADPH oxidase factor 2, p67-phox, p67-phox (rodent)

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat, mouse

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Ncf2(17970)
rat ... Ncf2(364018)

一般說明

Neutrophil cytosol factor 2 (UniProt Q09014; also known as 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, NADPH oxidase subunit 67 kDa, NCF-2, Ncf2, Neutrophil NADPH oxidase factor 2, p67-phox, p47phox) is encoded by the murine Ncf2 (also known as Noxa2, p67phox) gene in murine species (Gene ID 17970). Activation of NADPH-oxidase dependent superoxide generation requires the participation of several cytosolic factors, including p47-phox, p67-phox, p40-phox and Rac. In the resting cell p47phox, p67phox, and p40phox form a large molecular weight cytosolic complex. Activation of the NADPH oxidase is initiated by the assembly of p47phox, p67phox, and Rac with cytochrome b558 in a 1:1:1:1 complex in the plasma membrane.

免疫原

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of mouse p67-phox.

應用

Anti-p67-phox (not Human) Antibody is an antibody against p67-phox, tested in mouse and rat, but is not expected to react with human, for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected p67-phox (rodent) in rat colon and mouse hindbrain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in C6 and THP-1 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected p67-phox (rodent) in 10 µg of C6 and THP-1 cell lysate.

標靶描述

~72 kDa observed. Uncharacterized band(s) may appear in some lysates.

外觀

Affinity purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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