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Merck
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文件

07-324

Sigma-Aldrich

抗-PP2A抗体(C亚基 )

Upstate®, from rabbit

同義詞:

Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

bovine, rat, human, mouse

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... PPP2CA(5515)

特異性

PP2A催化亚基

免疫原

对应于人PP2A氨基酸290-304(DPAPRRGEPHVTRRT)的肽

應用

研究子类别
氧化应激

神经退行性疾病
研究类别
信号传导

神经科学
该抗-PP2A抗体(C亚基)经过验证可用于WB检测PP2A。

品質

已通过免疫印迹对小鼠脑、心脏、睾丸和肾脏匀浆液的RIPA裂解液进行常规评估

標靶描述

36kDa

外觀

0.2M Tris-甘氨酸(pH 7.4)、0.15M NaCl、0.05%叠氮化钠、5mg/ml BSA,然后添加甘油至30%
免疫亲和层析

儲存和穩定性

在-20°C下可保存2年

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

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存取文件庫

Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Shunya Tsuji et al.
The Journal of veterinary medical science, 81(10), 1424-1430 (2019-09-19)
Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase
Rongbin Hu et al.
Plant, cell & environment, 40(1), 150-164 (2016-10-28)
Protein phosphatase 2A (PP2A) is an enzyme consisting of three subunits: a scaffolding A subunit, a regulatory B subunit and a catalytic C subunit. PP2As were shown to play diverse roles in eukaryotes. In this study, the function of the
Ha Yin Lee et al.
Science signaling, 11(512) (2018-01-11)
Cancer cells increase glucose metabolism to support aerobic glycolysis. However, only some cancer cells are acutely sensitive to glucose withdrawal, and the underlying mechanism of this selective sensitivity is unclear. We showed that glucose deprivation initiates a cell death pathway

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