07-1401-AF488

Anti-GLUT-1 Antibody, CT, Alexa Fluor^™ 488 Conjugate

from rabbit, ALEXA FLUOR^™ 488

• 同義詞: Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, GLUT-1, CT, Alexa Fluor^™ 488 Conjugate
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 488
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: rat, mouse, human
• 物種活性（以同源性預測）: porcine (based on 100% sequence homology), bovine (based on 100% sequence homology), monkey (based on 100% sequence homology), feline (based on 100% sequence homology), equine (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable
• NCBI登錄號: NM_006516
• UniProt登錄號: P11166
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SLC2A1(6513)

描述

一般說明

Solute carrier family 2, facilitated glucose transporter member 1 (UniProt P11166; also known as Glucose transporter type 1 erythrocyte/brain, GLUT-1, HepG2 glucose transporter, Human T-cell leukemia virus I and II receptor, Receptor for HTLV-1 and HTLV-2) is encoded by the SLC2A1 (also known as DYT9, DYT17, DYT18, EIG12, GLUT, GLUT1, HTLVR, GLUT1DS, PED) gene (Gene ID 6513) in human. Glucose transporters (GLUT-1 to GLUT-7) constitute a family of integral membrane glycoproteins that facilitate cellular glucose uptake. In addition to mediateing glucose uptake in adult tissues, GLUT-1 is the predominant glucose transporter in embryonic and fetal tissues. Two forms of GLUT-1 are found in human frontal cortex, the 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.

特異性

This antibody recognizes GLUT-1.

免疫原

Epitope: C-terminus

Synthetic peptide corresponding amino acids with the C-terminus of human GLUT-1 coupled to KLH (C-ELFHPLGADSQV).

應用

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected GLUT-1 in HeLa and NIH/3T3 cells.
The unconjugated antibody (Cat. No. 07-1401) is shown to be suitable also for ELISA, Western blotting, immunocytochemistry, and immunohistochemistry applications.

Research Category
Signaling

Research Sub Category
Developmental Signaling

This Anti-GLUT-1 Antibody, CT, Alexa Fluor^™ 488 Conjugate is validated for use in Immunocytochemistry for the detection of GLUT-1.

品質

Evaluated by Immunocytochemistry in A431 cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GLUT-1 in A431 cells.

標靶描述

~54 kDa observed

外觀

Affinity purified

Purified rabbit conjugate antibody in PBS with 15 mg/ml BSA and 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2