06-1364

Anti-SRp30b (SC35) Antibody

from rabbit

• 同義詞: serine/arginine-rich splicing factor 2, Splicing factor SC35, Splicing component, 35 kDa, splicing factor, arginine/serine-rich 2, SR splicing factor 2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: human
• 技術: immunocytochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_001182356
• UniProt登錄號: Q01130
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SRSF2(6427)

描述

一般說明

SRp30b, also known as SC35, and Splicing factor, arginine/serine-rich 2 (SFRS2) is an essential splicing factor. This protein is encoded by the SFRS2 gene and is a member of the splicing factor SR family. SRp30b is involved in pre-mRNA splicing and is found in bodies in the nucleus that are highly enriched in poly(A) RNA. These nuclear bodies are referred to as speckles, SC 35 domains, or splicing factor compartments (SFCs). The purpose of these bodies is not completely characterized. Speckles correspond largely to, if not entirely to, ultra structures called inter-chromatin granule clusters (IGCs). SRp30b is required for pre-mRNA splicing events and is highly involved in spliceosomal interaction and assembly. This SR protein is necessary for assembly of the ATP-dependent splicing complex. It is also necessary for the ATP-dependent communication between pre-mRNA and U1 and U2 snRNPs.

免疫原

Linear peptide corresponding to human SRp30b.

應用

Anti-SRp30b (SC35) Antibody is a Rabbit Polyclonal Antibody for detection of SRp30b (SC35) also known as serine/arginine-rich splicing factor 2, Splicing factor SC35 & has been validated in WB, ICC.

Western Blot Analysis:
A 1:500 dilution of a representative lot of this antibody detected SRp30b in 10 µg of HeLa cell lysate.

Immunoprecipitation Analysis:
A representative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)

品質

Evaluated by Immunocytochemistry Analysis:
A 1:500 dilution of this antibody detected SRp30b in NIH/3T3 cells.

標靶描述

~35 kDa observed. Uncharacterized bands may be observed at ~10, 58, and 78 kDa

外觀

Format: Purified

分析報告

Control
NIH/3T3 cells.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable