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Merck
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05-682

Sigma-Aldrich

Anti-Mps1 Antibody, NT, clone 3-472-1

clone 3-472-1, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

3-472-1, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... C5AR2(27202)

一般說明

Mps1 was previously known as TTK/PYK

應用

Detect Mps1 with Anti-Mps1 Antibody, NT, clone 3-472-1 (Mouse Monoclonal Antibody), that has been shown to work in WB.

品質

routinely evaluated by immunoblot on HeLa total cell extract

標靶描述

97kDa

外觀

Format: Purified

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Mandar R Bhonde et al.
The Journal of biological chemistry, 281(13), 8675-8685 (2006-02-01)
DNA damage induced by the topoisomerase I inhibitor irinotecan (CPT-11) triggers in p53(WT) colorectal carcinoma cells a long term cell cycle arrest and in p53MUT cells a transient arrest followed by apoptosis (Magrini, R., Bhonde, M. R., Hanski, M. L.
Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.
Ballister, ER; Riegman, M; Lampson, MA
The Journal of cell biology null
Christopher P Mattison et al.
Cell cycle (Georgetown, Tex.), 10(5), 783-793 (2011-02-18)
The Mps1 family of protein kinases contributes to cell cycle control by regulating multiple microtubule cytoskeleton activities. We have uncovered a new Mps1 substrate that provides a novel link between Mps1 and the actin cytoskeleton. We have identified a conserved
Elodie Montaudon et al.
Nature communications, 11(1), 4053-4053 (2020-08-15)
A significant proportion of patients with oestrogen receptor (ER) positive breast cancers (BC) develop resistance to endocrine treatments (ET) and relapse with metastatic disease. Here we perform whole exome sequencing and gene expression analysis of matched primary breast tumours and
A Koch et al.
Oncogene, 35(19), 2518-2528 (2015-09-15)
Mps1/TTK is a dual-specificity kinase, with an essential role in mitotic checkpoint signaling, which has emerged as a potential target in cancer therapy. Several Mps1/TTK small-molecule inhibitors have been described that exhibit promising activity in cell culture and xenograft models.

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