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Merck
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04-298

Sigma-Aldrich

Anti-IGF1 Receptor (CT) Antibody, clone 7G11

clone 7G11, Upstate®, from mouse

同義詞:

insulin-like growth factor 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

7G11, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

ELISA: suitable
western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... IGF1(3479)

特異性

Recognizes C-terminus of IGF1 receptor

免疫原

KLH-conjugated synthetic peptide encompassing the surrounding amino acids of the C-terminus in human IGF1

應用

Anti-IGF1 Receptor (C-terminus) Antibody, clone 7G11 detects level of IGF1 Receptor (C-terminus) & has been published & validated for use in ELISA & WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

品質

Routinely evaluated by immunoblot.

標靶描述

90 kDa

外觀

Subsequent thiophilic adsorption and size exclusion chromatography
100 &mciro;g of purified mouse monoclonal IgG lyophilized in 2X PBS containing 0.09% sodium azide, PEG, and sucrose
Format: Purified

儲存和穩定性

2 years at -20°C from date of shipment. Reconstitute prior to use. Reconstitute with 1 mL H2O for 15 min at room temperature. Reconstituted aliquots should be stored frozen at -80°C. Thawed aliquots may be stored at 4°C for up to 3 months. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
Includes untreated A431 lysate as a positive control.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids


分析證明 (COA)

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Thomas Thum et al.
Circulation research, 100(3), 434-443 (2007-01-20)
Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age
M Wallander et al.
Diabetologia, 49(10), 2247-2255 (2006-09-07)
Low levels of IGF-I are associated with increased risk of cardiovascular disease and type 2 diabetes. The aim of this study was to investigate the IGF-I system in patients with acute myocardial infarction (AMI) without previously known diabetes. One hundred
Marcus H Borges et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(9), 2411-2419 (2019-06-09)
We have previously described regulation of syncytial GLUT1 glucose transporters by IGF-I. Despite this, it is not clear what signal regulates transplacental glucose transport. In this report we asked whether changes in GLUT1 expression and glucose transport activity in diabetic
Shuhua Chen et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(4), 1813-1824 (2020-07-08)
Previous studies demonstrated that the endogenous neurosteroid allopregnanolone (Allo) promotes regeneration of rodent and human neural progenitor/neural stem cells (NSCs) in vitro and in vivo, and restores neurogenesis and cognitive function in the male triple transgenic mouse model of Alzheimer's
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