R-013

利培酮-D_{4标准液 CRM} 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₃D₄H₂₃FN₄O₂
• CAS號碼: 1020719-76-9
• 分子量：: 414.51
• EC號碼: 200-659-6
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: [2H]C([2H])(N1CCC(CC1)c2noc3cc(F)ccc23)C([2H])([2H])C4=C(C)N=C5CCCCN5C4=O
• InChI: 1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3/i9D2,13D2
• InChI 密鑰: RAPZEAPATHNIPO-RIEWMPPISA-N

描述

一般說明

利培酮，以Risperdal^®、Ridal或Riscalin进行销售，是一种非典型抗精神病药，用于治疗自闭症儿童的精神分裂症、双相情感障碍和易怒症。这种新的内标适用于许多LC/MS和GC/MS应用，包括法医分析、临床毒理学、尿液药物测试或同位素稀释方法。

應用

• Efficacy and Safety Profiles of Antipsychotic Drugs as Viewed by Psychiatrists: This comparative analysis of cariprazine and risperiDonein clinical settings provides insights into the effectiveness and tolerability of risperidone, a tricyclic antidepressant, emphasizing its role in psychiatric treatment and drug development strategies (Gvozdeckii et al., 2023).


• Effect of Antipsychotics and Mood Stabilisers on Metabolism in Bipolar Disorder: A network meta-analysis focusing on the impact of medications like risperiDoneon metabolic profiles, crucial for understanding pharmacokinetic behaviors and optimizing therapeutic outcomes in bipolar disorder treatment (Kong et al., 2024).


• Antipsychotic Prescribing: National Findings of Children and Adolescents Attending Mental Health Services in Ireland: This study details the prescribing patterns of antipsychotics, including risperidone, contributing to a better understanding of its use in pediatric psychiatric care and aiding in the development of guidelines for safer and more effective use of antipsychotics in young populations (Driscoll and McCarthy, 2024).


• Antipsychotic Medications and Sleep Problems in Patients with Schizophrenia: Investigates the effects of antipsychotic drugs like risperiDoneon sleep disturbances among schizophrenia patients, supporting research into the comprehensive management of sleep issues associated with psychiatric disorders (Cederlöf et al., 2024).


• Hepatotoxicity to Risperidone: Discusses potential hepatotoxic effects of risperidone, highlighting the importance of monitoring liver function during treatment with this drug, essential for ensuring patient safety in clinical practices (André et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Risperdal is a registered trademark of Johnson & Johnson

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup