M-007

(+/-)-美沙酮标准液 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₁H₂₇NO
• CAS號碼: 76-99-3
• 分子量：: 309.45
• EC號碼: 200-659-6
• MDL號碼: MFCD00056289
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329817685
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)=O
• InChI: 1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3
• InChI 密鑰: USSIQXCVUWKGNF-UHFFFAOYSA-N
• 基因資訊: human ... OPRM1(4988)

描述

一般說明

美沙酮是一种合成阿片类药物，在医学上用作镇痛药和维持抗阿片类药物的药物，用于阿片类药物依赖性患者。该药以几种商品名出售，例如 Symoron、Dolophine^®、Amidone、Methadose^®、Physeptone 或 Heptadon。该认证的加标溶液适用于疼痛处方监测、法医分析或临床毒理学中的 LC/MS 或 GC/MS 测试方法。

應用

• Neurobehavioral and Molecular Changes in a Rodent Model: This study leverages Imipramine hydrochloride in a rodent model to investigate ACTH-induced HPA axis dysfunction, focusing on its effects on neurobehavior and molecular signaling pathways. This research underscores the utility of Imipramine hydrochloride in studying stress-related neuropsychiatric disorders, enhancing understanding of its therapeutic mechanisms in clinical settings (Sallie et al., 2024).


• Electrochemical DNA Biosensor Development: Imipramine hydrochloride is used in the development of novel electrochemical DNA biosensors, highlighting its role in enhancing the sensitivity and specificity of genetic analysis. This application is pivotal in biotechnological advancements for genomics and personalized medicine (Augustín et al., 2024).


• Diabetic Peripheral Neuropathy: Prevention and Treatment: Research incorporating Imipramine hydrochloride focuses on its effectiveness in managing symptoms of diabetic peripheral neuropathy, providing insights into its analgesic properties and mechanisms of action in nerve pain management, which is crucial for developing better therapeutic strategies (Bragg et al., 2024).


• Microvesicle Particles in Burn Injury: Utilizes Imipramine hydrochloride in a study investigating the role of microvesicle particles in mediating damage in burn injury cases, offering a new perspective on the systemic impacts of burn injuries and the potential interventions to mitigate these effects (Lohade et al., 2024).


• Sustainable Biosensor for Tricyclic Antidepressants: Highlights the use of Imipramine hydrochloride in the development of sustainable beeswax modified cellulose paper for the detection of tricyclic antidepressants in biofluids. This innovative approach represents a significant step forward in environmental sustainability and drug monitoring technologies (González-Bermúdez et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Dolophine is a registered trademark of Roxane Laboratories, Inc.

Methadose is a registered trademark of Mallinckrodt Inc.

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup