跳轉至內容
Merck
全部照片(1)

重要文件

查看所有文件

H-004

Supelco

氢吗啡酮标准液 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C17H19NO3
CAS號碼:
466-99-9
分子量：:
285.34
EC號碼:
200-659-6
MDL號碼:
MFCD00864214
分類程式碼代碼:
41116107
PubChem物質ID:
329815100
NACRES:
NA.24

等級

certified reference material

品質等級

300

形狀

liquid

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

濃度

1 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

形式

single component solution

儲存溫度

−20°C

SMILES 字串

CN1CC[C@@]23[C@H]4CCC(=O)[C@@H]2Oc5c(O)ccc(C[C@@H]14)c35

InChI

1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1

InChI 密鑰

WVLOADHCBXTIJK-YNHQPCIGSA-N

基因資訊

human ... OPRM1(4988)

尋找類似的產品？ 前往 產品比較指南

一般說明

该认证参考标准品适合用作校准品或对照品的原材料，用于从法医分析、临床毒理学、止痛药处方监测到尿液药物测试和药物研究等各种 LC/MS 或 GC/MS 应用。 氢吗啡酮，商品名为Palladone和Dilaudid®，是一种强效的阿片类镇痛药。该药通常在医学上用作吗啡的替代品，用于治疗疼痛或作为止咳药治疗持续性支气管刺激引起的疼痛性咳嗽。

應用


  • 氟哌啶醇的定量分析：研究人员开发了一种灵敏的LC-MS/MS方法用于定量测定人血浆中氟哌啶醇，该方法以氟哌啶醇-D₄为内标物，并结合磷脂去除预处理以提高检测准确性（Zidekova et al., 2021）。

  • 毒理学研究中的自动测定：氟哌啶醇-D₄在曲美布汀及其代谢产物毒代动力学研究的自动化方法中的应用，证明了化合物在高通量法医毒理学中的作用（Larabi et al., 2015）。

  • 高通量药物监测：高通量固相萃取和涡轮离子喷雾（turbo ionspray ）LC-MS-MS法在血浆中氟哌啶醇测定中的应用，展示了氟哌啶醇-D₄作为改进生物分析流程的稳定同位素标记标准品的效率（Hempenius et al., 1999）。



法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Dilaudid is a registered trademark of Purdue Pharma L.P.

相關產品

產品號碼
描述
訂價

H-010

Hydromorphone-D3 solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-006

Hydromorphone-D3 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P-071

13种疼痛管理混标 溶液, 100 μg/mL each component (10 μg/mL Fentanyl), ampule of 1.0 mL, certified reference material, Cerilliant®

H-049

Hydromorphone-D6 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-050

Hydromorphone-D6 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-051

Hydromorphone-3-β-D-glucuronide, 100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®

N-107

Norhydromorphone hydrochloride solution, 1.0 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®

H-004S

氢吗啡酮标准液 溶液, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Jessica R Barker et al.
Veterinary surgery : VS, 42(1), 79-84 (2012-12-12)
To evaluate efficacy of a topical epidural analgesia used alone, or in combination with hydromorphone, against a standard pain protocol for the 48 hours immediately after hemilaminectomy. Randomized, blinded, controlled, clinical trial. Dogs (n = 30) with thoracolumbar intervertebral disc disease
Leah C Stern et al.
Journal of the American Veterinary Medical Association, 241(3), 344-347 (2012-07-21)
To determine the frequency of postoperative vomiting in dogs undergoing routine orthopedic surgery that were treated with hydromorphone and whether that frequency would vary on the basis of administration route. Noncontrolled clinical trial. Animals-58 client-owned dogs with cranial cruciate ligament
Erik Rauch
AANA journal, 80(4 Suppl), S25-S32 (2012-12-20)
Despite compelling evidence for the safety and efficacy of intrathecal hydromorphone, the use of this opioid intrathecally for the pain management of patients undergoing cesarean delivery has not been widely accepted. The purpose of this retrospective study was to compare
Alec B O'Connor et al.
Journal of opioid management, 8(6), 403-413 (2012-12-25)
The reasons providers choose one parenteral opioid over another are not well understood. The authors sought to determine why emergency department (ED) providers choose one parenteral opioid over another. In a cohort of ED patients who received intravenous morphine or
Kyung Hee Lee et al.
Journal of opioid management, 8(4), 243-252 (2012-09-04)
To evaluate the effectiveness of OROS® hydromorphone in reducing breakthrough pain (BTP) medication frequency in Korean patients with chronic cancer pain. Multicenter, prospective, open-label, phase IV study. Patients with chronic malignant pain using immediate-release oxycodone more than two times per
查看所有相關論文

文章

Benefits of Ascentis Express Phenyl-Hexyl over Biphenyl for the Separation of Pain Management Opiates

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

條款

LC/MS (TOF) Analysis of Drugs and Their Glucuronide Metabolites in Urine on Titan™ C18 After Solid Phase Extraction (SPE) Using Supel™-Select SCX, β-Glucuronidase Enzyme Digestion

-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

使用UHPLC/MS（TOF）检测不同酶水解条件处理的尿液中药物和代谢物

为了使用β-葡糖醛酸酶优化水解，必须对每种待分析的葡糖苷酸代谢物进行某些因素的评估，例如孵育时间、温度、水解pH、酶源和酶浓度。

UHPLC/MS for Drug Detection in Urine

Optimize β-glucuronidase hydrolysis for glucuronide metabolite analysis considering factors like time, temperature, pH, and enzyme concentration.

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務