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D-033

Supelco

双氢吗啡标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

經驗公式（希爾表示法）:
C17H21NO3
CAS號碼:
509-60-4
分子量：:
287.35
EC號碼:
200-659-6
MDL號碼:
MFCD00190622
分類程式碼代碼:
41116107
PubChem物質ID:
329798599
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

形式

single component solution

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

O[C@@H](CC1)[C@@]2([H])[C@@]3([C@]1([H])[C@H](N(C)CC3)C4)C5=C4C=CC(O)=C5O2

InChI

1S/C17H21NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19-20H,3,5-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1

InChI 密鑰

IJVCSMSMFSCRME-KBQPJGBKSA-N

一般說明

Dihydromorphine is a semisynthetic opioid analgesic sold under the trade names Paramorfan or Paramorphan for treatment of pain. Dihydromorphine is also a primary active metabolite of the analgesic opioid drug dihydrocodeine. This Snap-N-Spike® Reference Solution is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from urine drug testing and pain prescription monitoring to pharmaceutical research.

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

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G Skopp et al.
Forensic science international, 95(2), 99-107 (1998-09-02)
A report of a fatal dihydrocodeine ingestion under substitution therapy is given. Quantitation of dihydrocodeine, dihydromorphine, N-nordihydrocodeine, dihydrocodeine-6-, dihydromorphine-6- and dihydromorphine-3-glucuronide was performed simultaneously after solid-phase extraction prior to HPLC analysis, and the analytes were detected using their native fluorescence.
Peter A Crooks et al.
Bioorganic & medicinal chemistry letters, 16(16), 4291-4295 (2006-06-17)
A series of 3-O-acyl-6-O-sulfate esters of morphine, dihydromorphine, N-methylmorphinium iodide, codeine, and dihydrocodeine were prepared and evaluated for their ability to bind to mu-, delta-, kappa(1)-, kappa(2)-, and kappa(3)-opiate receptors. Several compounds exhibited good affinity for the mu-opiate receptor. Morphine-3-O-propionyl-6-O-sulfate
Anna K Przybyl et al.
The Journal of organic chemistry, 68(5), 2010-2013 (2003-03-01)
A practical method for the conversion of tetrahydrothebaine to dihydromorphine in 92% yield is described. The procedure should allow more efficient production of opium products and may be easily modified for large-scale synthesis. The conversion of codeine to (8S)-8-bromomorphide, a
R Maggi et al.
European journal of pharmacology, 301(1-3), 169-177 (1996-04-22)
The present study showed that the glucocorticoid/progesterone antagonists, 17 beta-hydroxy-1 1 beta-(4-dimethylamino-phenyl-1)-17-(prop-1-ynyl)estra-4,9-dien+ ++-3-one (RU486) and 17 beta-hydroxy-11 beta-(4-dimethylamino-phenyl-1)-17-(propan-3-ol)estra-4,9-dien-3-o ne (ZK 98299), inhibit the binding of labeled dihydromorphine to mu-opioid receptors present on membrane preparations derived from rat and mouse brain
Annie-Kim Gilbert et al.
European journal of pharmacology, 492(2-3), 123-130 (2004-06-05)
The present study examined the pharmacology of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin (3,6-diacetyldihydromorphine). Like morphine, dihydromorphine and its acetylated derivatives all were highly selective mu-opioids in receptor binding assays. All the compounds were potent mu-selective analgesics, as shown by their sensitivity
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