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重要文件

890895P

Avanti

18:1 TAP(DOTAP,MS盐)

Avanti Research - A Croda Brand 890895P, powder

同義詞:

1,2-二油酰基-3-三甲基铵-丙烷 (硫酸甲酯盐)

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About This Item

經驗公式(希爾表示法):
C43H83NO8S
CAS號碼:
分子量::
774.19
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 2 × 100 mg (890895P-200mg)
pkg of 1 × 25 mg (890895P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 890895P

脂質類型

cationic lipids
transfection

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O

InChI

1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;

InChI 密鑰

RSMRWWHFJMENJH-LQDDAWAPSA-M

生化/生理作用

1,2-二油酰基-3-三甲基铵-丙烷(DOTAP)为阳离子脂质,用于体内体外核酸和蛋白递送。脂质组成和细胞类型会影响 DOTAP 的转染潜能。DOTAP介导造血干细胞(HSCs)的基因敲低技术。

包裝

5 mL透明玻璃密封安瓿(890895P-200mg)
5 mL透明玻璃密封安瓿(890895P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Critical reviews in therapeutic drug carrier systems, 21(4), 257-317 (2005-01-11)
Cationic lipid-mediated nucleic acid and protein delivery is becoming increasingly popular for in vitro and in vivo applications. While the chemistry of cationic lipid carriers is moving very rapidly, and more and more sophisticated molecules are being developed, it is
Bieong-Kil Kim et al.
Biochimica et biophysica acta, 1848(10 Pt A), 1996-2001 (2015-06-27)
The effects of lipid compositions on their physicochemical properties and transfection efficiencies were investigated. Four liposome formulations with different 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP) to dioleoylphosphatidylethanolamine (DOPE) weight ratios were investigated, that is, weight ratios 1:0 (T1P0), 3:1 (T3P1), 1:1 (T1P1), and 1:3

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