形狀
liquid
包裝
pkg of 1 × 1 mL (878115C-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand 878115C
濃度
5 mg/mL (878115C-5mg)
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O
一般說明
C16-04:0 PC, also known as 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine (butanoyl-PAF), is a platelet-activating factor (PAF) analog. It is synthesized non-enzymatically in the oxidized-low density lipoprotein (Ox-LDL) particles. Butanoyl-PAF is mainly produced in the body during high oxidative stress. This lipid mediator exhibits pro-inflammatory activity.
應用
C16-04:0 PC or 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine may be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.
包裝
5 mL Clear Glass Sealed Ampule (878115C-5mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
does not flash
閃點(°C)
does not flash
Sunil A Nankar et al.
Biochimie, 95(6), 1196-1207 (2013-02-05)
Apolipoprotein-derived peptides are promising candidates for the treatment of various inflammatory conditions and the main mechanism proposed for the protective action of these peptides includes binding to pro-inflammatory lipid mediators with high affinity and facilitating their sequestration/metabolism/clearance in the body.
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