全部照片(1)

文件

860675P

Avanti

Sphinganine-1-Phosphate (d20:0)

Name: Sphinganine-1-Phosphate (d20:0)
Brand: AVANTI

Avanti Research^™ - A Croda Brand 860675P, powder

同義詞:

D-erythro-sphinganine-1-phosphate (C20 base)

登入查看組織和合約定價

全部照片(1)

About This Item

經驗公式（希爾表示法）:

C₂₀H₄₄NO₅P

CAS號碼:

436846-91-2

分子量：:

409.54

分類程式碼代碼:

12352211

NACRES:

NA.25

推薦產品

Slide 1 of 10

1 of 10

Avanti

860498P

鞘氨醇 (d18:0)

Avanti

860490P

鞘氨醇 (d18:1)

Avanti

860536P

Sphinganine-1-Phosphate (d18:0)

Avanti

860674P

Sphinganine (d20:0)

Avanti

860492P

1-磷酸鞘氨醇 (d18:1)

Sigma-Aldrich

S7049

D-鞘氨醇

Avanti

860640P

鞘氨醇（d17:1）

Avanti

860516P

C16神经酰胺（d18:1/16:0）

Avanti

860518P

C18 神经酰胺 (d18:1/18:0)

Supelco

IMPC-051-03

副黄嘌呤标准液 CRM 溶液

形狀

powder

包裝

pkg of 1 × 1 mg (860675P-1mg)

製造商／商標名

Avanti Research^™ - A Croda Brand 860675P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](CCCCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C20H44NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h19-20,22H,2-18,21H2,1H3,(H2,23,24,25)/t19-,20+/m0/s1

InChI 密鑰

WEYZCBKZGOIPIU-VQTJNVASSA-N

一般說明

Sphinganine-1-Phosphate is a phosphorylated derivative of C20 base sphinganine.

生化／生理作用

Exogenous sphinganine-1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1). It exhibits protective effects against hepatic and renal ischemia and reperfusion (IR). Sphingosine-1 phosphate and sphinganine-1-phosphate are bioactive lipid mediators. Sphinganine-1-phosphate acts opposite to sphingosine-1 phosphate activities. Increased concentration of sphinganine-1-phosphate acts as a potential biomarker for fumonisin exposure and toxicity in mice.

包裝

5 mL Amber Glass Screw Cap Vial (860675P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

分析證明 (COA)

輸入產品批次/批號來搜索分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice.

Dong-Hyun Kim et al.

Journal of toxicology and environmental health. Part A, 69(23), 2071-2082 (2006-10-25)

Fumonisins are specific inhibitors of ceramide synthase in sphingolipid metabolism. An alteration in sphingolipid metabolism as a result of fumonisin B1 (FB1) exposure is related to cell death, and sphinganine/sphingosine ratio has been used as an indicator of fumonisin exposure

Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels.

Shizhong Bu et al.

Arthritis and rheumatism, 62(7), 2117-2126 (2010-03-24)

Previous studies have revealed a phosphatase and tensin homolog (PTEN)-dependent interaction between the sphingolipid agonist dihydrosphingosine 1-phosphate (dhS1P) and the transforming growth factor beta/Smad3 signaling pathway. This study was undertaken to examine responses of systemic sclerosis (SSc) fibroblasts to sphingosine

Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P1 receptor activation.

Sang Won Park et al.

Laboratory investigation; a journal of technical methods and pathology, 90(8), 1209-1224 (2010-05-12)

Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phosphate (S1P) levels. Furthermore, exogenous sphinganine-1-phosphate protected against both liver

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務

文件

Sphinganine-1-Phosphate (d20:0)