推薦產品
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 10 mg (860347P-10MG)
製造商/商標名
Avanti Research™ - A Croda Brand
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2
一般說明
Phosphatidylcholine (PC) (Lecithins) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH. The fatty acid in PC is mostly palmitic, stearic, oleic, linolenic and arachidonic acid. It is present abundantly in the mammalian membranes. PC is principally synthesized from cytidine diphosphate-choline (CDP-choline). Selective deuteration of this lipid may be used in the structural studies using techniques such as nuclear magnetic resonance (NMR), neutron reflectivity and small-angle neutron scattering.
生化/生理作用
Phosphatidylcholine (PC) is essential for cholesterol trafficking and membrane cholesterol homeostasis. It acts as the precursor for the synthesis of sphingomyelin. PC plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid.
包裝
5 mL Amber Glass Screw Cap Vial (860347P-10MG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Essentials of Medical Biochemistry (2011)
The Membranes of Cells (2016)
Phosphatidylcholine: greasing the cholesterol transport machinery
Lagace TA
Lipid insights, 8, LPI-S31746 (2015)
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric S, et al.
Applied Microbiology and Biotechnology, 99(1), 241-254 (2015)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
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