推薦產品
化驗
>99% (TLC)
形狀
powder
分子量
796.95 g/mol
包裝
pkg of 1 × 25 mg (850539P-25mg)
製造商/商標名
Avanti Research™ - A Croda Brand 850539P
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCOP(OCC[N+](C)(C)C)([O-])=O)([H])C[C@H](OCCOP(OCC[N+](C)(C)C)([O-])=O)[C@@]4(C)[C@@]1([H])CC[C@@H]4[C@H](C)CCC
應用
Facade™-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.
生化/生理作用
Facade™ EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.
Facade™ is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.
包裝
5 mL Amber Glass Screw Cap Vial (850539P-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Facade is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Faccade detergents as bicelle rim-forming agents for solution NMR spectroscopy
Nanotechnology Reviews, 6(1), 93-103 (2017)
Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding xenobiotic metabolism
Molecular Pharmacology, 89(4), 435-445 (2016)
Phase Transitions in Small Isotropic Bicelles
Langmuir, 34(11), 3426-3437 (2018)
Proceedings of the National Academy of Sciences of the United States of America, 110(13), E1203-E1211 (2013-03-13)
Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and
Designing facial amphiphiles for the stabilization of integral membrane proteins.
Angewandte Chemie (International ed. in English), 46(37), 7023-7025 (2007-08-11)
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