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Merck
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QBD10247

Sigma-Aldrich

Thiol-dPEG®4-acid

>95% (HPLC)

同義詞:

Carboxy-PEG4-thiol, HS-PEG4-COOH, Thiol-PEG-acid, Thiol-PEG4-COOH, Thiol-PEG4-acid

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About This Item

經驗公式(希爾表示法):
C11H22O6S
分子量::
282.35
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NA.22

化驗

>95% (HPLC)

形狀

solid or viscous liquid

反應適用性

reaction type: Pegylations

聚合物結構

shape: linear
functionality: heterobifunctional

運輸包裝

ambient

儲存溫度

−20°C

特點和優勢

Thiol-dPEG4-acid is a sulfhydryl-containing, crosslinking PEGylation reagent that has a cross-bridge of monodisperse polyethylene glycol. The single molecular weight, discrete-length PEG (dPEG) chain is 16 atoms (18.3 Å) long. The sulfhydryl end of the crosslinker reacts with gold (forming dative bonds) and with thiol-reactive functional groups such as maleimide, bromoacetyl, SPDP, and thiol. The carboxylic acid end of the molecule couples to free amines using EDC or any suitable carbodiimide. An acylating agent such as N-hydroxysuccinimide (NHS) or 2,3,5,6-tetrafluorophenol (TFP) can enhance coupling efficiency. The carboxylate must react after the sulfhydryl conjugation.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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