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H0751

Sigma-Aldrich

尿黑酸

crystalline

同義詞:

2,5-二羟基苯乙酸

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About This Item

線性公式:
(HO)2C6H3CH2CO2H
CAS號碼:
分子量::
168.15
Beilstein:
2692860
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

形狀

crystalline

顏色

off-white to tan

mp

150-152 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

OC(=O)Cc1cc(O)ccc1O

InChI

1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)

InChI 密鑰

IGMNYECMUMZDDF-UHFFFAOYSA-N

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一般說明

尿黑酸(HGA)是在苯丙氨酸和酪氨酸分解代谢过程中形成的中间产物。 尿黑酸尿症是一种代谢紊乱,其特征是血清和尿液含有高浓度的HGA,这是由于缺乏与HGA降解有关的尿黑酸氧化酶。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 5(4), 464-471 (1992-07-01)
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Free Radical Biology & Medicine, 3(4), 241-250 (1987)
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Archives internationales de physiologie, de biochimie et de biophysique, 102(3), 175-181 (1994-05-01)
Homogentisic acid (HGA) spontaneously starts to undergo oxidation and polymerization soon after the beginning of incubation in human blood or plasma at 37 degrees C, and forms plasma soluble melanins (PSM). Haemolysis accompanies this process in blood. The addition of
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Alkaptonuria (AKU) is a genetic disorder caused by lack of the enzyme responsible for breaking down homogentisic acid (HGA), an intermediate in tyrosine metabolism. HGA is deposited as a polymer, termed ochronotic pigment, in collagenous tissues. Pigmentation is progressive over
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Iron acquisition is critical to the growth and virulence of Legionella pneumophila. Previously, we found that L. pneumophila uses both a ferrisiderophore pathway and ferrous iron transport to obtain iron. We now report that two molecules secreted by L. pneumophila

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