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D120006

Sigma-Aldrich

2,6-二羟基吡啶 盐酸盐

97%

同義詞:

吡啶-2,6-二醇 盐酸盐

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About This Item

經驗公式(希爾表示法):
C5H5NO2 · HCl
CAS號碼:
分子量::
147.56
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

solid

mp

206-208 °C (dec.) (lit.)

SMILES 字串

Cl[H].Oc1cccc(O)n1

InChI

1S/C5H5NO2.ClH/c7-4-2-1-3-5(8)6-4;/h1-3H,(H2,6,7,8);1H

InChI 密鑰

HNWWAWKDVFVJRG-UHFFFAOYSA-N

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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H Stopper et al.
Biochemical and biophysical research communications, 203(2), 1124-1130 (1994-09-15)
The rate limiting step in 5-fluorouracil catabolism is catalyzed by the enzyme dihydropyrimidine dehydrogenase. Since degradation of 5-fluorouracil decreases its efficacy in chemotherapy, the inhibition of its catabolism is a promising tool. We investigated the formation of micronuclei in vitro
M Fukushima et al.
Gan to kagaku ryoho. Cancer & chemotherapy, 23(6), 721-731 (1996-05-01)
Possible pathways of intracellular phosphorylation of 5-fluorouracil (5-FU) in human cancer cells were investigated in vitro and in vivo. We used two inhibitors which regulate the anabolism of 5-FU for the purpose of elucidation of its pathways; one is oxonic
Paula Sachelaru et al.
Journal of bacteriology, 187(24), 8516-8519 (2005-12-03)
The enzyme catalyzing the hydrolytic cleavage of 2,6-dihydroxypseudooxynicotine to 2,6-dihydroxypyridine and gamma-N-methylaminobutyrate was found to be encoded on pAO1 of Arthrobacter nicotinovorans. The new enzyme answers an old question about nicotine catabolism and may be the first C--C bond hydrolase

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