V104

D-(+)-2-(4-苯基哌啶基)环己醇 盐酸盐

solid

• 經驗公式（希爾表示法）: C₁₇H₂₅NO · HCl
• CAS號碼: 112709-60-1
• 分子量：: 295.85
• MDL號碼: MFCD00069370
• 分類程式碼代碼: 12352005
• PubChem物質ID: 57654723
• NACRES: NA.22

屬性

• 形狀: solid
• 顏色: white
• 溶解度: DMSO: soluble; ethanol: soluble
• SMILES 字串: Cl.O[C@H]1CCCC[C@@H]1N2CCC(CC2)c3ccccc3
• InChI: 1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H/t16-,17-;/m0./s1
• InChI 密鑰: XJNUHVMJVWOYCW-QJHJCNPRSA-N

描述

一般說明

D-(+)-Vesamicol is a potent inhibitor of acetycholine transport into the synaptic vesicles in cholinergic nerve terminals. It is 25-times less potent than the L-form.

應用

D-(+)-Vesamicol hydrochloride can be used as a reactant to prepare:

• Trialkylstannyl vesamicol analogs as potent vesicular acetylcholine transporters (VAChTs) and sigma receptors.
• Vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino] cyclohexanol as a possible tumor imaging agent.

生化／生理作用

2-(4-苯基哌啶基)环己醇的活性较低的对映体

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H312 + H332
• 防範說明: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves